Speaker: Professor Matt Sweet.
Title: " Zinc as an antimicrobial weapon of the innate immune system".
Zinc is essential for immune function and maintenance of homeostasis. Macrophages are key cells of the innate immune system, providing frontline defence against infections. These "big-eaters" use pattern recognition receptors such as the toll-like receptors (TLRs) to detect and destroy invading microbes and other threats. This talk will provide an overview of the use of TLR-inducible zinc toxicity as a direct antimicrobial weapon of macrophages, as well as subversion of this pathway by bacterial pathogens. The use of bacterial reporter strains and dual single cell RNA sequencing of both host and pathogen to both track and delineate novel players in this antimicrobial pathway will also be described.
Zoom meeting details are:
https://deakin.zoom.us/j/
Meeting ID: 879 9577 1833
Password: 73448819
Contact: Leigh Ackland; Meeting organizer of ISZB-Asia/Oceania: leigh.
To be held:
5 pm Australia/Melbourne time (this is 6pm AEDT Australian Daylight Saving Time. Zoom is using AEST so log in at 6pm, not 5pm)
4 pm Japan/Tokyo time
3 pm China/Beijing time
3 pm Taipei/Taiwan time
8 am London time
9 am European time
3 am US EDT
7 pm New Zealand time (this is 7 pm New Zealand Standard Time but 8 pm Daylight Saving Time. Zoom is using New Zealand Standard Time so log in at 8 pm, not 7 pm)